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Review
. 2014 Mar 16;5(4):281-90.
doi: 10.7150/jca.8016. eCollection 2014.

Current approaches and challenges in early detection of breast cancer recurrence

Erika J Schneble  1 , Lindsey J Graham  1 , Matthew P Shupe  1 , Frederick L Flynt  1 , Kevin P Banks  1 , Aaron D Kirkpatrick  1 , Aviram Nissan  2 , Leonard Henry  3 , Alexander Stojadinovic  4 , Nathan M Shumway  1 , Itzhak Avital  4 , George E Peoples  1 , Robert F Setlik  1
Affiliations
Review

Current approaches and challenges in early detection of breast cancer recurrence

Erika J Schneble et al. J Cancer. .

Abstract

Early detection of breast cancer recurrence is a key element of follow-up care and surveillance after completion of primary treatment. The goal is to improve survival by detecting and treating recurrent disease while potentially still curable assuming a more effective salvage surgery and treatment. In this review, we present the current guidelines for early detection of recurrent breast cancer in the adjuvant setting. Emphasis is placed on the multidisciplinary approach from surgery, medical oncology, and radiology with a discussion of the challenges faced within each setting.

Keywords: Adjuvant; Breast cancer; Follow-up; Recurrence; Surveillance.

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Conflict of interest statement

Competing Interests: The authors have declared that no competing interest exists.

References

    1. Parkin DM, Fernandez LM. Use of statistics to assess the global burden of breast cancer. The breast journal. 2006;12(Suppl 1):S70–80. doi:10.1111/j.1075-122X.2006.00205.x. - PubMed
    1. van der Sangen MJ, Poortmans PM, Scheepers SW, Lemaire BM, van Berlo CL, Tjan-Heijnen VC. et al. Prognosis following local recurrence after breast conserving treatment in young women with early breast cancer. Eur J Surg Oncol. 2013;39:892–8. doi:S0748-7983(13)00375-2 [pii]10.1016/j.ejso.2013.05.004. - PubMed
    1. Lu WL, Jansen L, Post WJ, Bonnema J, Van de Velde JC, De Bock GH. Impact on survival of early detection of isolated breast recurrences after the primary treatment for breast cancer: a meta-analysis. Breast Cancer Res Treat. 2009;114:403–12. doi:10.1007/s10549-008-0023-4. - PubMed
    1. Rosselli Del Turco M, Palli D, Cariddi A, Ciatto S, Pacini P, Distante V. Intensive diagnostic follow-up after treatment of primary breast cancer. A randomized trial. National Research Council Project on Breast Cancer follow-up. JAMA. 1994;271:1593–7. - PubMed
    1. Investigators TG. Impact of follow-up testing on survival and health-related quality of life in breast cancer patients. A multicenter randomized controlled trial. The GIVIO Investigators. JAMA. 1994;271:1587–92. - PubMed