ADAMTS13, TTP and Beyond
- PMID: 24790789
- PMCID: PMC4001087
- DOI: 10.4172/2161-1041.1000e104
ADAMTS13, TTP and Beyond
Keywords: ADAMTS; Atherosclerosis; Inflammation; Thrombosis; Thrombotic thrombocytopenic purpura; Von willebrand factor cleaving protease.
Conflict of interest statement
Author has no competing financial interests.
References
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- Levy GG, Nichols WC, Lian EC, Foroud T, McClintick JN, et al. Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura. Nature. 2001;413:488–494. - PubMed
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- Zheng X, Chung D, Takayama TK, Majerus EM, Sadler JE, et al. Structure of von Willebrand factor-cleaving protease (ADAMTS13), a metalloprotease involved in thrombotic thrombocytopenic purpura. J Biol Chem. 2001;276:41059–41063. - PubMed
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- Dong JF, Moake JL, Nolasco L, Bernardo A, Arceneaux W, et al. ADAMTS-13 rapidly cleaves newly secreted ultralarge von Willebrand factor multimers on the endothelial surface under flowing conditions. Blood. 2002;100:4033–4039. - PubMed
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