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. 2014 May;39(2):109-14.
doi: 10.5395/rde.2014.39.2.109. Epub 2014 Mar 21.

Antibacterial properties of composite resins incorporating silver and zinc oxide nanoparticles on Streptococcus mutans and Lactobacillus

Shahin Kasraei  1 , Lida Sami  2 , Sareh Hendi  3 , Mohammad-Yousef Alikhani  4 , Loghman Rezaei-Soufi  5 , Zahra Khamverdi  1
Affiliations

Antibacterial properties of composite resins incorporating silver and zinc oxide nanoparticles on Streptococcus mutans and Lactobacillus

Shahin Kasraei et al. Restor Dent Endod. 2014 May.

Abstract

Objectives: Recurrent caries was partly ascribed to lack of antibacterial properties in composite resin. Silver and zinc nanoparticles are considered to be broad-spectrum antibacterial agents. The aim of the present study was to evaluate the antibacterial properties of composite resins containing 1% silver and zinc-oxide nanoparticles on Streptococcus mutans and Lactobacillus.

Materials and methods: Ninety discoid tablets containing 0%, 1% nano-silver and 1% nano zinc-oxide particles were prepared from flowable composite resin (n = 30). The antibacterial properties of composite resin discs were evaluated by direct contact test. Diluted solutions of Streptococcus mutans (PTCC 1683) and Lactobacillus (PTCC 1643) were prepared. 0.01 mL of each bacterial species was separately placed on the discs. The discs were transferred to liquid culture media and were incubated at 37℃ for 8 hr. 0.01 mL of each solution was cultured on blood agar and the colonies were counted. Data was analyzed with Kruskall-Wallis and Mann-Whitney U tests.

Results: Composites containing nano zinc-oxide particles or silver nanoparticles exhibited higher antibacterial activity against Streptococcus mutans and Lactobacillus compared to the control group (p < 0.05). The effect of zinc-oxide on Streptococcus mutans was significantly higher than that of silver (p < 0.05). There were no significant differences in the antibacterial activity against Lactobacillus between composites containing silver nanoparticles and those containing zinc-oxide nanoparticles.

Conclusions: Composite resins containing silver or zinc-oxide nanoparticles exhibited antibacterial activity against Streptococcus mutans and Lactobacillus.

Keywords: Anti-bacterial agents; Composite resin; Nanoparticles; Silver; Zinc oxide.

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Conflict of interest statement

No potential conflict of interest relevant to this article was reported.

Figures

Figure 1
Figure 1
SEM-EDX image of the surface of the composite resin samples containing 1% of silver and zinc-oxide nanoparticles.
See this image and copyright information in PMC

References

    1. Opdam NJ, Bronkhorst EM, Roeters JM, Loomans BA. A retrospective clinical study on longevity of posterior composite and amalgam restorations. Dent Mater. 2007;23:2–8. - PubMed
    1. Sadowsky SJ. An overview of treatment considerations for esthetic restorations: a review of the literature. J Prosthet Dent. 2006;96:433–442. - PubMed
    1. Pereira-Cenci T, Cenci MS, Fedorowicz Z, Marchesan MA. Antibacterial agents in composite restorations for the prevention of dental caries. Cochrane Database Syst Rev. 2009;(3):CD007819. - PubMed
    1. Papagiannoulis L, Kakaboura A, Eliades G. In vivo vs in vitro anticariogenic behavior of glass-ionomer and resin composite restorative materials. Dent Mater. 2002;18:561–569. - PubMed
    1. Thomé T, Mayer MP, Imazato S, Geraldo-Martins VR, Marques MM. In vitro analysis of inhibitory effects of the antibacterial monomer MDPB-containing restorations on the progression of secondary root caries. J Dent. 2009;37:705–711. - PubMed

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