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Review
. 2014 Jan;40(1):12-7.
doi: 10.12865/CHSJ.40.01.02. Epub 2013 Dec 29.

Pharmacological mechanisms underlying the association of antipsychotics with metabolic disorders

Ileana Cristina Miron  1 , Victoriţa Cătălina Baroană  1 , Florica Popescu  2 , Floriana Ionică  3
Affiliations
Review

Pharmacological mechanisms underlying the association of antipsychotics with metabolic disorders

Ileana Cristina Miron et al. Curr Health Sci J. 2014 Jan.

Abstract

Obesity and metabolic syndrome in association with an increased risk of cardiovascular disease and type II diabetes are significant problems that contribute to lower life expectancy of patients with schizophrenia. Understanding the pharmacological mechanisms of the current antipsychotic treatment is clearly the key to the improvement of pharmacotherapy, to avoid or to mitigate the metabolic adverse effects.

Keywords: antipsychotic; metabolic disorders; pharmacological mechanisms.

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