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. 2014 Jan;40(1):27-36.
doi: 10.12865/CHSJ.40.01.05. Epub 2013 Dec 29.

Plasma levels of glucose and insulin in patients with brain tumors

Oana Alexandru  1 , L Ene  1 , Oana Stefana Purcaru  2 , Daniela Elise Tache  2 , Alisa Popescu  3 , Oana Maria Neamtu  4 , Ligia Gabriela Tataranu  5 , Ada Maria Georgescu  6 , Valerica Tudorica  1 , Cornelia Zaharia  1 , Anica Dricu  2
Affiliations

Plasma levels of glucose and insulin in patients with brain tumors

Oana Alexandru et al. Curr Health Sci J. 2014 Jan.

Abstract

In the last years there were many authors that suggest the existence of an association between different components of metabolic syndrome and various cancers. Two important components of metabolic syndrome are hyperglycemia and hyperinsulinemia. Both of them had already been linked with the increased risk of pancreatic, breast, endometrial or prostate cancer. However the correlation of the level of the glucose and insulin with various types and grades of brain tumors remains unclear. In this article we have analysed the values of plasma glucose and insulin in 267 patients, consecutively diagnosed with various types of brain tumors. Our results showed no correlation between the glycemia and brain tumor types or grades. High plasma levels of insulin were found in brain metastasis and astrocytomas while the other types of brain tumors (meningiomas and glioblastomas) had lower levels of the peptide. The levels of insulin were also higher in brain metastasis and grade 3 brain tumors when compared with grade 1, grade 2 and grade 4 brain tumors.

Keywords: brain tumors; glucose; insulin; relations.

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Figures

Fig. 1
Fig. 1
Types of studied brain tumors
Fig. 2
Fig. 2
Grades of studied brain tumors
Fig. 3
Fig. 3
The correlation between brain tumors types and age of the patients
Fig. 3
Fig. 3
The correlation between brain tumors types and age of the patients
Fig. 4
Fig. 4
The correlation between brain tumors grade and age of the patients
Fig. 4
Fig. 4
The correlation between brain tumors grade and age of the patients
Fig. 5
Fig. 5
The correlation between brain tumors types and the values of glycemia
Fig. 5
Fig. 5
The correlation between brain tumors types and the values of glycemia
Fig. 6
Fig. 6
The correlation between brain tumors grade and the values of plasma glycemia
Fig. 6
Fig. 6
The correlation between brain tumors grade and the values of plasma glycemia
Fig. 7
Fig. 7
The correlation between brain tumor types and values of plasma insulin
Fig. 7
Fig. 7
The correlation between brain tumor types and values of plasma insulin
Fig. 8
Fig. 8
The correlation between brain tumors grades and the values of plasma insulin
Fig. 8
Fig. 8
The correlation between brain tumors grades and the values of plasma insulin
Fig. 9
Fig. 9
The correlation between brain tumors origin tissue and the values of plasma insulin
See this image and copyright information in PMC

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