Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2014 May 2:2014:bcr2014204035.
doi: 10.1136/bcr-2014-204035.

Neutropenic enterocolitis affecting the transverse colon: an unusual complication of chemotherapy

Affiliations
Case Reports

Neutropenic enterocolitis affecting the transverse colon: an unusual complication of chemotherapy

Jason Ramsingh et al. BMJ Case Rep. .

Abstract

A 66-year-old woman presented with a 1-day history of sudden onset of generalised abdominal pain associated with fever and vomiting. She was previously diagnosed with left breast cancer 2 months ago and completed a course of chemotherapy 1 week prior to presentation. She was clinically unwell with generalised tenderness in her abdomen. Blood investigations showed severe neutropenia. A CT scan was requested which reported a marked oedematous swelling of the transverse colon with features suggestive of a contained perforation. The decision was made to operate. Intraoperatively, the transverse colon was found to be thickened with omentum adherent focally around the distal third. A right hemicolectomy was performed with an end ileostomy and mucus fistula. The patient made a successful recovery and was discharged within 7 days of presenting. Pathology reported typical features of neutropenic enterocolitis affecting the transverse colon with a normal terminal ileum, caecum and ascending colon.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Coronal section illustrating markedly oedematous transverse colon with contained perforation.

References

    1. Song HK, Kreisel D, Canter R, et al. Changing presentation and management of neutropenic enterocolitis. Arch Surg 1998;133:979–82 - PubMed
    1. Gorschluter M, Mey U, Strehl J, et al. Neutropenic enterocolitis in adults: systematic analysis of evidence quality. Eur J Haematol 2005;75:1–13 - PubMed
    1. Mullassery D, Bader A, Battersby A, et al. Diagnosis, incidence and outcomes of suspected typhlitis in oncology patients—exoerience in a tertiary surgical centre in the United Kingdom. J Pediatr Surg 2009;44:381–5 - PubMed
    1. Alt B, Glass NR, Sollinger H. Neutropenic enterocolitis in adults: review of the literature and assessment of surgical intervention. Am J Surg 1985;149:405–8 - PubMed
    1. Katz JA, Wagner ML, Gresik MV, et al. Typhilitis: an 18 year experience and post mortum review. Cancer 1990;65:1041–7 - PubMed

Publication types

MeSH terms