Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2014 May 2:2014:bcr2014204456.
doi: 10.1136/bcr-2014-204456.

A single injection of intravitreal ranibizumab in the treatment of choroidal neovascularisation secondary to optic nerve head drusen in a child

Zeynep Alkin  1 , Abdullah Ozkaya, Ihsan Yilmaz, Ahmet Taylan Yazici
Affiliations
Case Reports

A single injection of intravitreal ranibizumab in the treatment of choroidal neovascularisation secondary to optic nerve head drusen in a child

Zeynep Alkin et al. BMJ Case Rep. .

Abstract

Optic nerve head drusen are acellular, calcified deposits which may be found in buried or exposed drusen form. Choroidal neovascularisation secondary to optic nerve head drusen is rarely seen in childhood. This case report summarises the clinical and therapeutic outcomes of a 13-year-old girl with unilateral choroidal neovascularisation secondary to optic nerve head drusen. The patient was successfully treated with a single intravitreal ranibizumab injection. After a month from the injection the visual acuity increased dramatically and maintained at the same level during 9 months of follow-up time. There was no complication related to the injection.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Fundus photo of the right and left eye (A and B). Arrow indicates yellow elevation in the papillomacular area (A). Autofluorescence images of the right and left eye (C and D), fluorescein angiographies of the right and left eye (E and F), spectral domain optical coherence tomography of the right and left eye (G and H).
Figure 2
Figure 2
Spectral domain optical coherence tomography of the right eye before the treatment (A), at month 1 (B), at month 3 (C) and at month 9 (D).
See this image and copyright information in PMC

References

    1. Rodriguez PF, Gili P, Rios MDM. Ophthalmic features of optic disc drusen. Ophthalmologica 2012;228:59–66 - PubMed
    1. Auw-Haedrich C, Staubach F, Witschel H. Optic disk drusen. Surv Ophthalmol 2002;47:515–32 - PubMed
    1. Delyfer M, Rougier M, Fourmaux E, et al. Laser photocoagulation for choroidal neovascular membrane associated with optic disc drusen. Acta Ophthalmol Scand 2004;82:236–8 - PubMed
    1. Adan A, Corcóstegui B. Surgical removal of peripapillary choroidal neovascularization associated with optic nerve drusen. Retina 2004;24:739–45 - PubMed
    1. Torrent R, Loureiro R, Travassos A, et al. Bilateral CNV associated with optic nerve drusen treated with photodynamic therapy with verteporfin. Eur J Ophthalmol 2004;14:434–7 - PubMed

Publication types