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Comment
. 2014 May 1;14(5):555-6.
doi: 10.1016/j.stem.2014.04.008.

Induced hematopoietic stem cells: unlocking restrictions in lineage potential and self-renewal

Martin Wahlestedt  1 , David Bryder  2
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Induced hematopoietic stem cells: unlocking restrictions in lineage potential and self-renewal

Martin Wahlestedt et al. Cell Stem Cell. .
Free article

Abstract

Obtaining sufficient numbers of immunologically matched hematopoietic stem cells (HSCs) poses a major clinical hurdle in bone marrow transplantation therapies. In a recent study in Cell, Riddell et al. (2014) generate induced HSCs from differentiated blood cells, which may serve as a potential solution to this clinical challenge.

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