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Review
. 2014 May;32(2):293-8.
doi: 10.1016/j.ccl.2013.12.003. Epub 2014 Jan 30.

Indications for cardiac resynchronization therapy

Thomas M O'Brien  1 , Edward J Schloss  1 , Eugene S Chung  2
Affiliations
Review

Indications for cardiac resynchronization therapy

Thomas M O'Brien et al. Cardiol Clin. 2014 May.

Abstract

Initial studies established patient selection criteria for cardiac resynchronization therapy (CRT) as left ventricular ejection fraction less than or equal to 35%, QRS greater than or equal to 120 ms, and New York Heart Association 3-4. Based on newer data, post hoc analyses, and meta-analyses, these criteria have been refined and guidelines updated, highlighting left bundle branch morphology and QRS greater than 150 ms in selecting patients with a likelihood of favorable outcomes. Guidelines will change as more data become available; the decision to apply CRT should be based on patient clinical profile and the balance of risk tolerance and likelihood of benefit.

Keywords: Biventricular pacing; Cardiac resynchronization therapy; Dyssynchrony; Heart failure.

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