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Case Reports
. 2014 Aug;20(8):926-8.
doi: 10.1016/j.parkreldis.2014.04.003. Epub 2014 Apr 14.

Cardiac sympathetic denervation without Lewy bodies in a case of multiple system atrophy

G A Cook  1 , P Sullivan  2 , C Holmes  2 , D S Goldstein  2
Affiliations
Case Reports

Cardiac sympathetic denervation without Lewy bodies in a case of multiple system atrophy

G A Cook et al. Parkinsonism Relat Disord. 2014 Aug.
No abstract available

Keywords: Alpha-synuclein; Catecholaldehyde; DOPAL; MSA; Multiple system atrophy; Parkinson disease.

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Figures

Fig. 1
Fig. 1
18F-DOPA (top and blow-up in middle) and 18F-dopamine (bottom) PET scans in control subjects (left) and in the current patient with MSA (right). There is neuroimaging evidence for decreased, distorted putamen 18F-DOPA-derived radioactivity and markedly decreased cardiac sympathetic innervation.
See this image and copyright information in PMC

References

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    1. Goldstein DS, Sullivan P, Holmes C, Miller GW, Alter S, Strong R, et al. Determinants of buildup of the toxic dopamine metabolite DOPAL in Parkinson’s disease. J Neurochem. 2013;126:591–603. - PMC - PubMed

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