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. 1989 Nov 6;257(2):247-50.
doi: 10.1016/0014-5793(89)81544-3.

Prothymosin alpha is an evolutionary conserved protein covalently linked to a small RNA

T Makarova  1 , N Grebenshikov, C Egorov, A Vartapetian, A Bogdanov
Affiliations
Free article

Prothymosin alpha is an evolutionary conserved protein covalently linked to a small RNA

T Makarova et al. FEBS Lett. .
Free article

Abstract

A 13 kDa protein, covalently linked to a small RNA from the cytoplasm of mouse cells, was studied. Sequence analysis of its tryptic peptides revealed that the RNA-linked protein is identical to prothymosin alpha. Very similar RNA-protein complexes were identified in human, bovine and yeast cells. Tryptic peptide maps of 125I-labelled RNA-linked proteins of diverse origin demonstrated their marked similarity, thus indicating high evolutionary conservation of prothymosin alpha from yeast to man.

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