Catalysis by the RNA subunit of RNase P--a minireview
- PMID: 2479591
- DOI: 10.1016/0378-1119(89)90030-9
Catalysis by the RNA subunit of RNase P--a minireview
Abstract
RNase P, an enzyme that contains both RNA and protein components, cleaves tRNA precursors to generate mature 5' termini. The catalytic activity of RNase P resides in the RNA component, with the protein cofactor affecting the rate of the cleavage reaction. The reaction is also influenced by the nature of the tRNA substrate.
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