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Randomized Controlled Trial
. 2014 Jul;41(7):673-80.
doi: 10.1111/jcpe.12268. Epub 2014 Jun 1.

The effect of periodontal therapy on glycaemic control in a Hispanic population with type 2 diabetes: a randomized controlled trial

Isabel C Gay  1 , Duong T Tran, Adriana C Cavender, Robin Weltman, Jennifer Chang, Estelle Luckenbach, Gena D Tribble
Affiliations
Randomized Controlled Trial

The effect of periodontal therapy on glycaemic control in a Hispanic population with type 2 diabetes: a randomized controlled trial

Isabel C Gay et al. J Clin Periodontol. 2014 Jul.

Abstract

Objective: In the Mexican-American population, the prevalence of Type 2 diabetes mellitus (T2DM) is as high as 50% of the population. This randomized controlled clinical trial was designed to elucidate how treatment of periodontal disease affects HbA1c values in this population.

Materials and methods: One hundred and fifty-four T2DM patients with periodontal disease were enrolled in the study. The test group was treated with scaling and root planing (SRP); the control group received oral hygiene instructions. At baseline and 4-6 weeks after therapy, a complete periodontal examination was performed. Blood was collected at baseline and 4 months later for HbA1c levels.

Results: One hundred and twenty-six individuals completed the study. Baseline mean ± SD HbA1c for the test and control groups were 9.0 ± 2.3% and 8.4 ± 2.0% respectively. Non-significant difference in HbA1c reductions (0.6 ± 2.1% and 0.3 ± 1.7%) was found between test and control groups at 4 months. Comparisons of the periodontal clinical parameters between the test and control groups found significant differences with improved results in the test subjects.

Conclusions: No statistically significant differences were found in the changes of HbA1c levels between test and control groups. Non-surgical periodontal therapy improved the magnitude of change in periodontal parameters as compared to the control subjects. ClinicalTrials.gov Identifier: NCT01128374.

Keywords: HbA1c; Hispanic population; periodontitis; scaling and root planing; type 2 diabetes mellitus.

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