Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 1989 Nov 25;2(8674):1248-9.
doi: 10.1016/s0140-6736(89)91853-9.

Augmentation of rat liver regeneration by FK 506 compared with cyclosporin

A Francavilla  1 , M Barone, S Todo, Q Zeng, K A Porter, T E Starzl
Affiliations
Comparative Study

Augmentation of rat liver regeneration by FK 506 compared with cyclosporin

A Francavilla et al. Lancet. .

Abstract

The immunosuppressive drug, FK 506, increased the regeneration response that follows 40% and 70% hepatectomy in rats. The effect was similar to that obtained with cyclosporin.

PubMed Disclaimer

References

    1. Gonzalez EM, Krejczy K, Malt RA. Modification of nucleic acid synthesis in regenerating liver by azathioprine. Surgery. 1970;68:254–259. - PubMed
    1. Guzek JW. Effect of adrenocorticotrophic hormone and cortisone on the uptake of tritated thymidine by regnerating liver tissue in the white rat. Nature. 1964;201:930–931. - PubMed
    1. Makowka L, Svanas G, Esquivel C, et al. The effect of cyclosporine on hepatic regeneration. Surg Forum. 1986;37:352–354. - PMC - PubMed
    1. Kahn D, Lai HS, Romovacek H, Makowka L, Van Thiel D, Starzl TE. Cyclosporin A augments the regeneration response after partial hepatectomy in the rat. Transplant Proc. 1988;20 suppl 3:850–852. - PMC - PubMed
    1. Kim YI, Calne RY, Nagasue N. Cyclosporine A stimulates proliferation of the liver cells after partial hepatectomy in rats. Surg Gynecol Obstet. 1988;166:317–322. - PubMed

Publication types