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. 2014 Jul-Aug;38(4):458-463.
doi: 10.1016/j.clinimag.2014.03.013. Epub 2014 Mar 30.

Is diffusion-weighted imaging a significant indicator of the development of vascularization in hypovascular hepatocellular lesions?

Kenichi Takara  1 , Kazuhiro Saito  2 , Toru Saguchi  1 , Katsutoshi Sugimoto  3 , Junichi Taira  3 , Yasuharu Imai  3 , Fuminori Moriyasu  3 , Soichi Akata  1 , Koichi Tokuuye  1
Affiliations

Is diffusion-weighted imaging a significant indicator of the development of vascularization in hypovascular hepatocellular lesions?

Kenichi Takara et al. Clin Imaging. 2014 Jul-Aug.

Abstract

Objective: The objective was to evaluate the efficacy of diffusion-weighted imaging (DWI) in predicting the development of vascularization in hypovascular hepatocellular lesions (HHLs).

Materials and methods: Forty-two HHLs that were diagnosed by computed tomographic (CT) arteriography were evaluated retrospectively. The lesion on DWI was classified as isointense, hypointense, or hyperintense. Follow-up studies that included intravenous dynamic CT or magnetic resonance imaging were performed.

Results: The 730-day cumulative developments of vascularization in hypointense, isointense, and hyperintense lesions were 17%, 30%, and 40%, respectively. The differences among these developments were not statistically significant.

Conclusion: The signal intensity on DWI showed no significant difference in the development of vascularization.

Keywords: Development of vascularization; Diffusion-weighted imaging; Gd-EOB-DTPA; Hepatocellular carcinoma; Hypovascular hepatocellular nodule.

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