Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2013 Oct;23(5):531-5.

Posterior Urethral Valves; A single Center Experience

Alireza Mirshemirani  1 , Ahmad Khaleghnejad  1 , Mohsen Rouzrokh  1 , Afsaneh Sadeghi  2 , Leila Mohajerzadeh  1 , Mustafa Sharifian  3
Affiliations

Posterior Urethral Valves; A single Center Experience

Alireza Mirshemirani et al. Iran J Pediatr. 2013 Oct.

Abstract

Objective: Posterior urethral valves (PUV) are the most common cause of bladder outlet obstruction in infancy that impair renal and bladder function. This study was planned to evaluate and record the various clinical presentations and management, complications, and surgical management and long-term outcome of PUV.

Methods: In a retrospective study, 98 patients who have been treated for PUV are evaluated in Mofid Children's Hospital from January 2007 to December 2012. Detailed history taken and paraclinical examinations were performed in each patient and diagnosis was confirmed by voiding-cysto-urethrography (VCUG). PUV had been ablated in 62 patients by electric hook, and diversion was performed in 42 (42.85%) cases. Data were analyzed by SPSS software version18.

Findings: Totally 98 patients with mean age at diagnosis 62 (±13) days were included in this study. Fifty seven cases had been catheterized within one to 6 days of life (mean age one day), PUV was ablated in 62 patients by electric hook, and diversion was performed in 42 cases. The most common symptom in our group was dribbling poor stream 51% and urinary tract infection (UTI) 40.8%. There was vesico-ureteral-reflux (VUR) in 61.2%, and hydronephrosis in 82.6%. Most common associated anomaly was kidney anomalies (multicystic kidney disease and renal agenesis/dysplasia) in 8 (8.2%) patients. Twenty patients had prenatal diagnosis of PUV. Complication occurred in three (3.1%) patients. Mortality occurred in 5 (5.1%) patients. Mean follow-up period was 3.4±1.2 years (1.5 months to 5 years).

Conclusion: Urinary drainage by feeding tube in early days of infancy, followed by valve ablation is the best treatment in PUV, and urinary diversion improves the outcome. VCUG is still the gold-standard imaging modality for documenting PUVs. The factors like renal dysplasia and UTI have their role in final outcome.

Keywords: Children; Outcome; PUV; Urinary Diversion; Urinary Drainage; Valve Ablation.

PubMed Disclaimer

References

    1. Smith GH, Canning DA, Schulman SL. Long-term outcome of posterior urethral valves treated with primary valve ablation and observation. J Urol. 1996;155(5):1730–4. - PubMed
    1. Malik MA, Javed Sial SH, Iqbal Z, et al. Posterior urethral valves. Professional Med J. 2005;12(4):473–8.
    1. Hutton KAR. Management of posterior urethral valves. Curr Pediatr. 2004;14:568–75.
    1. Hendren WH. Posterior urethral valves in boys, a broad clinical spectrum. J Urol. 1971;106(2):298–307. - PubMed
    1. Ricci Z, Curz DN, Ronco C. Classification and staging of acute kidney injury: beyond the RIFLE and AKIN criteria. Nat Rev Nephrol. 2011;7(4):201–8. - PubMed

LinkOut - more resources