Cell biology: ESCRTing trouble out!
- PMID: 24801189
- DOI: 10.1016/j.cub.2014.03.044
Cell biology: ESCRTing trouble out!
Abstract
Calcium entry through a plasma membrane defect leads to the local recruitment of endosomal complex required for transport (ESCRT) proteins. These proteins are hypothesized to drive an outward bending of the affected plasma membrane, forming a small bud that is then shed from the cell, along with the troublesome defect.
Copyright © 2014 Elsevier Ltd. All rights reserved.
Comment on
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ESCRT machinery is required for plasma membrane repair.Science. 2014 Feb 28;343(6174):1247136. doi: 10.1126/science.1247136. Epub 2014 Jan 30. Science. 2014. PMID: 24482116
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