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Review
. 2014 May;141(10):1983-6.
doi: 10.1242/dev.104596.

Adult neurogenesis: mechanisms and functional significance

Simon M G Braun  1 , Sebastian Jessberger
Affiliations
Free article
Review

Adult neurogenesis: mechanisms and functional significance

Simon M G Braun et al. Development. 2014 May.
Free article

Abstract

New neurons are generated throughout life in distinct regions of the mammalian brain. This process, called adult neurogenesis, has been implicated in physiological brain function, and failing or altered neurogenesis has been associated with a number of neuropsychiatric diseases. Here, we provide an overview of the mechanisms governing the neurogenic process in the adult brain and describe how new neurons may contribute to brain function in health and disease.

Keywords: Neural stem cell; Neurogenesis; Neurons; Neuropsychiatric disease.

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