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Clinical Trial
. 2014 May 7;20(17):5087-91.
doi: 10.3748/wjg.v20.i17.5087.

Value of a new stick-type rapid urine test for the diagnosis of Helicobacter pylori infection in the Vietnamese population

Duc T Quach  1 , Toru Hiyama  1 , Fumio Shimamoto  1 , Quang D Le  1 , Linh X Ho  1 , Nhu Ht Vu  1 , Masaharu Yoshihara  1 , Naomi Uemura  1
Affiliations
Clinical Trial

Value of a new stick-type rapid urine test for the diagnosis of Helicobacter pylori infection in the Vietnamese population

Duc T Quach et al. World J Gastroenterol. .

Abstract

Aim: To assess the value of a new test for the diagnosis of Helicobacter pylori (H. pylori) infection, Rapirun H. pylori Antibody Stick (Rapirun Stick), in a Vietnamese population.

Methods: Eligible patients without previous history of H. pylori eradication were recruited. Rapid urease test (RUT) and histologic examination were used to diagnose the H. pylori infection. Patients were considered H. pylori positive when the RUT results were positive and/or the bacteria were detected histologically. Rapirun Stick tests were performed using urine samples, and the results were compared with the other 2 methods.

Results: We enrolled 200 patients with a mean age of 36 (range, 18-76) years. There were 116 females and 84 males. Of the 200 patients, 111 (55.5%) were diagnosed as being H. pylori positive. The sensitivity, specificity, and accuracy of the Stick test were 84.7%, 89.9%, and 87.0%, respectively. There were 17 (8.5%) false-negative patients and 9 (4.5%) false-positive patients.

Conclusion: The Rapirun Stick test has high sensitivity, specificity, and accuracy for the diagnosis of H. pylori infection in the Vietnamese population. The test can be clinically applied in Vietnamese populations.

Keywords: Helicobacter pylori; Rapid urease test; Rapirun® Stick; Urine test; Vietnamese.

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Figures

Figure 1
Figure 1
Rapirun® Helicobacter pylori Antibody Stick. The sample is considered positive when 2 red bands at the test line and control line (arrows) are observed 15 min later and is considered negative when only the control line is observed. The absence of a control line indicates an invalid result.
See this image and copyright information in PMC

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