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. 2014 Aug;76(8):1157-60.
doi: 10.1292/jvms.13-0349. Epub 2014 May 8.

A study on Borna disease virus infection in domestic cats in Japan

Azusa Someya  1 , Ryoko Fukushima, Michiko Yoshida, Yasuyuki Tanahashi, Tangmunkhong Prapeuk, Reiko Iizuka, Hiroshi Hirami, Atsushi Matsuda, Shunichi Takahashi, Goro Kurita, Takashi Kimura, Misuzu Seo, Masayuki Funaba, Yoshii Nishino
Affiliations

A study on Borna disease virus infection in domestic cats in Japan

Azusa Someya et al. J Vet Med Sci. 2014 Aug.

Abstract

Borna disease virus (BDV) infection causes neurological disease in cats. Here, we report BDV infection in 199 hospitalized domestic cats in the Tokyo area. BDV infection was evaluated by detection of plasma antibodies against BDV-p24 or -p40. BDV-specific antibodies were detected in 54 cats (27.1%). Interestingly, the percentage of seropositive cats was not significantly different among the three clinical groups, i.e., healthy (29.8%), neurologically asymptomatic disease (22.2%) and neurological disease (33.3%). The specific antibodies were present even in cats aged below one year. The seropositive ratio was constant, irrespective of age and sampling season. The present study suggests that additional factors are required for onset of Borna disease in naturally infected cats and that BDV is transmitted through vertical routes in cats.

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