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Review
. 1989 Sep;12(9):349-53.
doi: 10.1016/0166-2236(89)90042-8.

Glycine modulation of the NMDA receptor/channel complex

Review

Glycine modulation of the NMDA receptor/channel complex

A M Thomson. Trends Neurosci. 1989 Sep.

Abstract

One class of excitatory amino acid (EAA) receptor, the N-methyl-D-aspartate (NMDA) receptor, has excited enormous interest because of its unique pharmacological and physiological properties. Yet another property of this receptor/channel complex has recently emerged: its activation is greatly enhanced by and may even be dependent on, sub-micromolar concentrations of glycine.

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