doi: 10.1016/0167-4781(89)90115-2.
Characteristic sequences in the upstream region of the human tyrosinase gene
Affiliations
- PMID: 2480811
- DOI: 10.1016/0167-4781(89)90115-2
Item in Clipboard
Characteristic sequences in the upstream region of the human tyrosinase gene
Biochim Biophys Acta.
.
Abstract
A human tyrosinase gene containing a 5'-flanking region and the first exon was isolated from a normal human liver library using mouse tyrosinase cDNA as a probe for screening. In the 5'-upstream region of transcriptional start sites, there is a putative TATA box and CAAT box and some palindromic sequences. A characteristic sequence of (GA:TCn, which can assume a hinged-DNA structure, was present from -869 nt to -633 nt in this 5'-flanking region.
Similar articles
-
Isolation, chromosomal mapping, and expression of the mouse tyrosinase gene.J Invest Dermatol. 1989 Nov;93(5):589-94. doi: 10.1111/1523-1747.ep12319693. J Invest Dermatol. 1989. PMID: 2507645
-
Human oculocutaneous albinism caused by single base insertion in the tyrosinase gene.Biochem Biophys Res Commun. 1989 Nov 15;164(3):990-6. doi: 10.1016/0006-291x(89)91767-1. Biochem Biophys Res Commun. 1989. PMID: 2511845
-
Molecular analysis of the DNA segments cross-hybridizable to the tyrosinase gene in patients affected with oculocutaneous albinism.Tohoku J Exp Med. 1989 Dec;159(4):333-40. doi: 10.1620/tjem.159.333. Tohoku J Exp Med. 1989. PMID: 2517365
-
A study of murine albinism using tyrosinase cDNA.Prog Clin Biol Res. 1988;256:263-71. Prog Clin Biol Res. 1988. PMID: 3130638 No abstract available.
-
Gene correction by RNA-DNA oligonucleotides.Pigment Cell Res. 2000 Apr;13(2):72-9. doi: 10.1034/j.1600-0749.2000.130205.x. Pigment Cell Res. 2000. PMID: 10841028 Review.
Cited by
-
A nonsense mutation in the tyrosinase gene of Afghan patients with tyrosinase negative (type IA) oculocutaneous albinism.J Med Genet. 1991 Jul;28(7):464-7. doi: 10.1136/jmg.28.7.464. J Med Genet. 1991. PMID: 1832718 Free PMC article.
-
Dinucleotide repeat polymorphism at the human tyrosinase gene.Nucleic Acids Res. 1991 Dec 25;19(24):6968. doi: 10.1093/nar/19.24.6968. Nucleic Acids Res. 1991. PMID: 1762935 Free PMC article. No abstract available.
-
Selective in-vitro Enzymes' Inhibitory Activities of Fingerprints Compounds of Salvia Species and Molecular Docking Simulations.Iran J Pharm Res. 2020 Spring;19(2):187-198. doi: 10.22037/ijpr.2020.112498.13801. Iran J Pharm Res. 2020. PMID: 33224224 Free PMC article.
-
A tyrosinase gene missense mutation in temperature-sensitive type I oculocutaneous albinism. A human homologue to the Siamese cat and the Himalayan mouse.J Clin Invest. 1991 Mar;87(3):1119-22. doi: 10.1172/JCI115075. J Clin Invest. 1991. PMID: 1900309 Free PMC article.
-
The tyrosinase-related protein-1 gene has a structure and promoter sequence very different from tyrosinase.Nucleic Acids Res. 1991 Jul 25;19(14):3799-804. doi: 10.1093/nar/19.14.3799. Nucleic Acids Res. 1991. PMID: 1907365 Free PMC article.
Publication types
MeSH terms
Substances
Associated data
- Actions
LinkOut - more resources
Full Text Sources
Other Literature Sources
Molecular Biology Databases
Research Materials
