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. 2014 Apr 12:8:27-9.
doi: 10.1016/j.gynor.2014.03.004. eCollection 2014 Apr.

Invasive extramammary Paget's disease of the bladder diagnosed 18 years after noninvasive extramammary Paget's disease of the vulva

Affiliations

Invasive extramammary Paget's disease of the bladder diagnosed 18 years after noninvasive extramammary Paget's disease of the vulva

Cherry O Onaiwu et al. Gynecol Oncol Case Rep. .
No abstract available

Keywords: Bladder cancer; Extramammary Paget's disease; Paget's disease of vulva.

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Figures

Fig. 1
Fig. 1
A) Cervix (H&E, 4 ×) demonstrating a concentration of Paget cells in the basal layer; B) higher power image (H&E, 20 ×) shows the large Paget cells with abundant, eosinophilic cytoplasm with a slightly eccentric nucleus.
Fig. 2
Fig. 2
A) Bladder biopsy (H&E, 4 ×) with increased cellularity involving the full tissue thickness; B) higher power image (H&E, 20 ×) shows the cellular proliferation to be composed of eosinophilic cells with eccentric nuclei; C) the cells are diffusely, and strongly cytokeratin 7 positive; and D) negative cytokeratin 20 stain.

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References

    1. Hegarty P.K. Penoscrotal extramammary Paget's disease: the University of Texas M. D. Anderson Cancer Center contemporary experience. J. Urol. 2011;186(1):97–102. - PubMed
    1. Inoue S., Shiina H., Igawa M. Paget's disease of the vulva with bladder invasion: a case report. Arch. Gynecol. Obstet. 2012;285(5):1493–1496. - PubMed
    1. Kay J.M., Southwood W.F. Paget's disease of the vulva associated with an unusual bladder tumour. Br. J. Cancer. 1964;18:233–237. - PMC - PubMed
    1. Koga F., Gotoh S., Suzuki S. A case of invasive bladder cancer with Pagetoid skin lesion of the vulva and anogenital Paget's disease. Nihon Hinyokika Gakkai Zasshi. 1997;88(4):503–506. - PubMed
    1. Kuroda J., Takemura T., Kanokogi M. A case of Paget's disease of the vulva with bladder metastasis. Hinyokika Kiyo. 1987;33(5):774–778. - PubMed

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