Comparative Study
[The effect of antihistamine preparations on the contraction of the isolated guinea pig ureter]
[Article in
Russian]
- PMID: 2480912
Item in Clipboard
Comparative Study
[The effect of antihistamine preparations on the contraction of the isolated guinea pig ureter]
[Article in
Russian]
Farmakol Toksikol.
1989 Sep-Oct.
Abstract
The effect of antihistaminics on contractions of the isolated guinea pig ureter was studied. The ureter contractions induced by histamine were prevented by H1-blockers: pipolphen (promethazine), dimedrol (diphenhydramine), phencarol (quifenadine), suprastin (chloropyramine), cyproheptadine and H2-blockers: cimetidine, ranitidine. Electric stimulation-induced contractions were prevented by suprastin. Phencarol, tavegil, cimetidine, ranitidine didn't act on the contractions. The electrically induced contractions were potentiated by pipolphen, dimedrol, cyproheptadine.
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