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. 1989 Dec 14;342(6251):762-6.
doi: 10.1038/342762a0.

Primary structure and functional expression from complementary DNA of the rod photoreceptor cyclic GMP-gated channel

U B Kaupp  1 , T Niidome, T Tanabe, S Terada, W Bönigk, W Stühmer, N J Cook, K Kangawa, H Matsuo, T Hirose, et al.
Affiliations

Primary structure and functional expression from complementary DNA of the rod photoreceptor cyclic GMP-gated channel

U B Kaupp et al. Nature. .

Abstract

The complete amino-acid sequence of the cyclic GMP-gated channel from bovine retinal rod photoreceptors, deduced by cloning and sequencing its complementary DNA, shows that the protein contains several putative transmembrane segments, followed by a region that is similar to the cyclic GMP-binding domains of cyclic GMP-dependent protein kinase. Expression of the complementary DNA produces cyclic GMP-gated channel activity in Xenopus oocytes.

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