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. 2014 Jun;43(2):317-27.
doi: 10.1016/j.gtc.2014.02.013.

Eosinophilic gastroenteritis and related eosinophilic disorders

Calman Prussin  1
Affiliations

Eosinophilic gastroenteritis and related eosinophilic disorders

Calman Prussin. Gastroenterol Clin North Am. 2014 Jun.

Abstract

Eosinophilic gastroenteritis (EGE) represents one member within the spectrum of diseases collectively referred to as eosinophilic gastrointestinal disorders, which includes eosinophilic esophagitis (EoE), gastritis, enteritis, and colitis. EGE is less common than EoE and involves a different site of disease but otherwise shares many common features with EoE. The clinical manifestations of EGE are protean and can vary from nausea and vomiting to protein-losing enteropathy or even bowel obstruction requiring surgery. Although systemic corticosteroids are an effective treatment for EGE, their use results in substantial corticosteroid toxicity. Accordingly, there is a great need for improved therapies for these patients.

Keywords: EGID; Eosinophilia; Eosinophilic gastritis; Eosinophilic gastroenteritis; Food allergy.

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Conflict of interest statement

Disclosures:

The author has no competing financial interests.

Figures

Figure 1
Figure 1
Duodenal biopsy showing intense areas of eosinophilic inflammation.
Figure 2
Figure 2
Gastric pseudopolyps involving the gastric antrum and pyloris
Figure 3
Figure 3
Pseudopolyps within the terminal ileum.
See this image and copyright information in PMC

References

    1. Spergel JM, Book WM, Mays E, et al. Variation in prevalence, diagnostic criteria, and initial management options for eosinophilic gastrointestinal diseases in the United States. Journal of pediatric gastroenterology and nutrition. 2011;52(3):300–306. - PMC - PubMed
    1. Naylor AR. Eosinophilic gastroenteritis. Scottish medical journal. 1990;35(6):163–165. - PubMed
    1. Talley NJ, Shorter RG, Phillips SF, et al. Eosinophilic gastroenteritis: a clinicopathological study of patients with disease of the mucosa, muscle layer, and subserosal tissues. Gut. 1990;31(1):54–58. - PMC - PubMed
    1. Kelly KJ. Eosinophilic gastroenteritis. Journal of pediatric gastroenterology and nutrition. 2000;30(Suppl):S28–S35. - PubMed
    1. Khan S. Eosinophilic gastroenteritis. Best practice & research Clinical gastroenterology. 2005;19(2):177–198. - PubMed

Supplementary concepts