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Randomized Controlled Trial
. 2014 Aug;47(2):140-5.
doi: 10.1016/j.jsat.2014.03.004. Epub 2014 Apr 4.

Reasons for opioid use among patients with dependence on prescription opioids: the role of chronic pain

Roger D Weiss  1 , Jennifer Sharpe Potter  2 , Margaret L Griffin  3 , R Kathryn McHugh  3 , Deborah Haller  4 , Petra Jacobs  5 , John Gardin 2nd  6 , Dan Fischer  7 , Kristen D Rosen  8
Affiliations
Randomized Controlled Trial

Reasons for opioid use among patients with dependence on prescription opioids: the role of chronic pain

Roger D Weiss et al. J Subst Abuse Treat. 2014 Aug.

Abstract

The number of individuals seeking treatment for prescription opioid dependence has increased dramatically, fostering a need for research on this population. The aim of this study was to examine reasons for prescription opioid use among 653 participants with and without chronic pain, enrolled in the Prescription Opioid Addiction Treatment Study, a randomized controlled trial of treatment for prescription opioid dependence. Participants identified initial and current reasons for opioid use. Participants with chronic pain were more likely to report pain as their primary initial reason for use; avoiding withdrawal was rated as the most important reason for current use in both groups. Participants with chronic pain rated using opioids to cope with physical pain as more important, and using opioids in response to social interactions and craving as less important, than those without chronic pain. Results highlight the importance of physical pain as a reason for opioid use among patients with chronic pain.

Keywords: Chronic pain; Opioid analgesics; Opioid dependence; Prescription drug abuse; Relapse.

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References

    1. American Psychiatric Association . Diagnostic and statistical manual of mental disorders. 4th ed. American Psychiatric Association; Washington, DC: 1994.
    1. Anton RF, O'Malley SS, Ciraulo DA, Cisler RA, Couper D, Donovan DM, Zweben A. Combined pharmacotherapies and behavioral interventions for alcohol dependence: the COMBINE study: a randomized controlled trial. The Journal of the American Medical Association. 2006;295:2003–2017. doi: 10.1001/jama.295.17.2003. - PubMed
    1. Back SE, Lawson KM, Singleton LM, Brady KT. Characteristics and correlates of men and women with prescription opioid dependence. Addictive Behaviors. 2011;36:829–834. doi:10.1016/j.addbeh.2011.03.013. - PMC - PubMed
    1. Barth KA, Maria MM, Lawson K, Shaftman S, Brady KT, Back SE. Pain and motives for use among non-treatment seeking individuals with prescription opioid dependence. American Journal on Addictions. 2013;22:486–491. doi:10.1111/j.1521-0391.2013.12038.x. - PMC - PubMed
    1. Boyd CJ, McCabe SE, Cranford JA, Young A. Adolescents' motivations to abuse prescription medications. Pediatrics. 2006;1118:2472–2480. doi: 10.1542/peds.2006-1644. - PMC - PubMed

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