Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2014 Apr;3(2):97-100.
doi: 10.4103/2278-330X.130441.

Breast carcinoma in young females below the age of 40 years: A histopathological perspective

Affiliations

Breast carcinoma in young females below the age of 40 years: A histopathological perspective

Shitalmala Thangjam et al. South Asian J Cancer. 2014 Apr.

Abstract

Background: Breast cancer among young women is a rare pathology, but is known to have a more aggressive behavior and poorer outcome.

Aims: The objective of this study was to evaluate the clinicopathological characteristics of breast carcinoma below 40 years in comparison to that over 40 years in Manipur, India.

Settings and design: This retrospective study from the period of January 2005-December 2010 was conducted in the Department of Pathology, Regional Institute of Medical Sciences, Imphal, Manipur.

Materials and methods: All cases of mastectomy specimens of carcinoma breast from the period of January 2005-December 2010 were included in the study. Clinical and histopathological data of all cases were reviewed and correlated.

Results: A total of 507 mastectomy specimens were received, among which, 160 cases (31.56%) were below 40 years; whereas 347 cases (68.44%) were above 40 years of age. Stage III was the commonest stage (47% versus 18%) in the younger group; while in the older group, Stage II was the commonest (64% versus 34%).

Conclusion: This study shows that young females with breast cancer have higher stage of tumor.

Keywords: Breast cancer; TNM staging of breast cancer; histopathology; mastectomy; young.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest: None declared.

Similar articles

Cited by

References

    1. Colleoni M, Rotmensz N, Robertson C, Orlando L, Viale G, Renne G, et al. Very young women (<35 years) with operable breast cancer: Features of disease at presentation. Ann Oncol. 2002;13:273–9. - PubMed
    1. El Saghir NS, Seoud M, Khalil MK, Charafeddine M, Salem ZK, Geara FB, et al. Effects of young age at presentation on survival in breast cancer. BMC Cancer. 2006;6:194. - PMC - PubMed
    1. Ntekim A, Nufu FT, Campbell OB. Breast cancer in young women in Ibadan, Nigeria. Afr Health Sci. 2009;9:242–6. - PMC - PubMed
    1. Kim JK, Kwak BS, Lee JS, Hong SJ, Kim HJ, Son BH, et al. Do very young Korean breast cancer patients have worst outcome? Ann Surg Oncol. 2007;14:3385–91. - PubMed
    1. Swanson GM, Lin CS. Survival patterns among younger women with breast cancer: The effects of age, race, stage, and treatment. J Natl Cancer Inst Monogr. 1994;16:69–77. - PubMed