Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2014 May;65(5):443-9.
doi: 10.1007/s00105-013-2699-6.

[Drug reactions caused by chemotherapy agents]

[Article in German]
L M Ehmann  1 , H Schrumpf, P A Gerber, B Homey
Affiliations
Review

[Drug reactions caused by chemotherapy agents]

[Article in German]
L M Ehmann et al. Hautarzt. 2014 May.

Abstract

In recent years, several new classes of compounds have successfully been established in the treatment of cancer. They selectively inhibit disturbed signaling pathways or induce anti-tumor immune responses. These novel targeted cancer drugs show a favorable safety profile compared to conventional chemotherapeutic agents. The most important side effects of these anticancer agents include cutaneous reactions and occur in a time-dependant manner and show class-specific patterns. In this review article, we compare the cutaneous side effects of epidermal growth factor inhibitors (EGFRI), multikinase inhibitors (MKI), BRAF inhibitors (BRAFI), mTor inhibitors (mTorI) and immune checkpoint inhibitors and discuss severity-adapted management strategies.

PubMed Disclaimer

References

    1. J Dtsch Dermatol Ges. 2011 Apr;9(4):277-86 - PubMed
    1. J Dtsch Dermatol Ges. 2012 Aug;10(8):559-63 - PubMed
    1. N Engl J Med. 2012 Feb 2;366(5):480-1 - PubMed
    1. N Engl J Med. 2012 Jun 28;366(26):2443-54 - PubMed
    1. J Am Acad Dermatol. 2013 Nov;69(5):708-720 - PubMed

MeSH terms

Substances

LinkOut - more resources