[Analysis of the treatment of pseudomyxoma peritonei--cytoreductive surgery with chemotherapy and intraperitoneal inoculation after washing with dextran]

Abstract

Twelve cases of pseudomyxoma peritonei in the Department of Obstetrics and Gynecology in Kurume University School of Medicine were categorized in three groups by treatment; 3 cases with just operations, 6 cases with chemotherapies after operations and 3 cases with chemotherapies and intraperitoneal inoculations of cisplatin after washing with dextran. These treatments were analyzed by their survival rates. As to the cases repeated operations, the second look laparotomy was estimated as a cytoreductive surgery, including a prior chemotherapy. Ten of 13 chemotherapeutic courses were effective in the 6 cases with second look laparotomies and five of 6 cases were living without tumor. We confirm the treatment of the intraperitoneal inoculation of cisplatin after dextrose washing with the cytoreductive surgery is one of the most effective therapies for pseudomyxoma peritonei.