Assessing correlates of protection in vaccine trials
- PMID: 24823622
- DOI: 10.1093/infdis/jiu283
Assessing correlates of protection in vaccine trials
Keywords: Zostavax; correlate of protection; herpes zoster; principal stratification; subgroups; surrogate outcome; vaccine efficacy.
Comment on
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Fold rise in antibody titers by measured by glycoprotein-based enzyme-linked immunosorbent assay is an excellent correlate of protection for a herpes zoster vaccine, demonstrated via the vaccine efficacy curve.J Infect Dis. 2014 Nov 15;210(10):1573-81. doi: 10.1093/infdis/jiu279. Epub 2014 May 13. J Infect Dis. 2014. PMID: 24823623 Free PMC article. Clinical Trial.
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