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. 2014 Mar 26;70(Pt 4):o476-7.
doi: 10.1107/S1600536814006199. eCollection 2014 Apr 1.

{2-[(2-Hy-droxy-benzyl-idene)amino]-4,5,6,7-tetra-hydro-1-benzo-thio-phen-3-yl}(phen-yl)methanone

Manpreet Kaur  1 , Jerry P Jasinski  2 , Channappa N Kavitha  1 , H S Yathirajan  1 , K Byrappa  3
Affiliations

{2-[(2-Hy-droxy-benzyl-idene)amino]-4,5,6,7-tetra-hydro-1-benzo-thio-phen-3-yl}(phen-yl)methanone

Manpreet Kaur et al. Acta Crystallogr Sect E Struct Rep Online. .

Abstract

In the title compound, C22H19NO2S, the cyclo-hexene ring adopts a slightly distorted half-chair conformation. The dihedral angles between the mean planes of the thio-phene ring and the phenyl and 2-hy-droxy-phenyl rings are 70.4 (5) and 12.1 (9)°, respectively. The phenyl and 2-hy-droxy-phenyl rings are twisted with respect to one another by 81.0 (6)°. A short intra-molecular O-H⋯N hydrogen bond is observed. In the crystal, weak C-H⋯O inter-actions link the mol-ecules into zigzag chains diagonally along [100] .

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Figures

Fig. 1.
Fig. 1.
ORTEP drawing of (I) (C22H19NO2S) showing the labeling scheme of molecule with 30% probability displacement ellipsoids. The dashed line indicates a short O2—H2···N1 intramolecular hydrogen bond.
Fig. 2.
Fig. 2.
Molecular packing for (I) viewed along the c axis. Dashed lines indicate weak intermolecular C—H···O interactions which link the molecules into zig-zag chains along [101]. H atoms not involved in these weak intermolecular interactions have been removed for clarity.
See this image and copyright information in PMC

References

    1. Agilent (2012). CrysAlis PRO and CrysAlis RED Agilent Technologies, Yarnton, England.
    1. Allen, F. H., Kennard, O., Watson, D. G., Brammer, L., Orpen, A. G. & Taylor, R. (1987). J. Chem. Soc. Perkin Trans. 2, pp. S1–19.
    1. Asthalatha, B. V., Narayana, B., Vijaya Raj, K. K. & Kumari, N. S. (2007). Eur. J. Med. Chem. 42, 719–728. - PubMed
    1. Aydogan, F., Ocal, N., Turgut, Z. & Yolacan, C. (2001). Bull. Korean Chem. Soc. 22, 476–480.
    1. Cannito, A., Perrisin, M., Luu-Duc, C., Huguer, F., Gaultier, C. & Narcisse, G. (1990). Eur. J. Med. Chem. 25, 635–639.