Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2014:2014:781926.
doi: 10.1155/2014/781926. Epub 2014 Mar 11.

Inverted (Reverse) Takotsubo Cardiomyopathy following Cerebellar Hemorrhage

Sophie Piérard  1 , Marco Vinetti  1 , Philippe Hantson  2
Affiliations

Inverted (Reverse) Takotsubo Cardiomyopathy following Cerebellar Hemorrhage

Sophie Piérard et al. Case Rep Cardiol. 2014.

Abstract

Background. First described in 2005, inverted takotsubo is one of the four stress-induced cardiomyopathy patterns. It is rarely associated with subarachnoid hemorrhage but was not previously reported after intraparenchymal bleeding. Purpose. We reported a symptomatic case of inverted takotsubo pattern following a cerebellar hemorrhage. Case Report. A 26-year-old woman presented to the emergency department with sudden headache and hemorrhage of the posterior fossa was diagnosed, probably caused by a vascular malformation. Several hours later, she developed acute pulmonary edema due to acute heart failure. Echocardiography showed left ventricular dysfunction with hypokinetic basal segments and hyperkinetic apex corresponding to inverted takotsubo. Outcome was spontaneously favorable within a few days. Conclusion. Inverted takotsubo pattern is a stress-induced cardiomyopathy that could be encountered in patients with subarachnoid hemorrhage and is generally of good prognosis. We described the first case following a cerebellar hematoma.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Admission electrocardiogram.
Figure 2
Figure 2
Transthoracic echocardiogram (4-chamber view) during end-diastole (a) and end-systole (b) shows basal and midventricular segmental hypokinesis (dotted line for reduced shortening) of the left ventricle (LV), with a well-preserved apical segmental systolic function (loop).
See this image and copyright information in PMC

References

    1. Song BG, Chun WJ, Park YH, et al. The clinical characteristics, laboratory parameters, electrocardiographic, and echocardiographic findings of reverse or inverted Takotsubo cardiomyopathy: comparison with mid or apical variant. Clinical Cardiology. 2011;34(11):693–699. - PMC - PubMed
    1. Ramaraj R, Movahed MR. Reverse or inverted Takotsubo cardiomyopathy (reverse left ventricular apical ballooning syndrome) presents at a younger age compared with the mid or apical variant and is always associated with triggering stress. Congestive Heart Failure. 2010;16(6):284–286. - PubMed
    1. Movahed M-R, Mostafizi K. Reverse or inverted left ventricular apical ballooning syndrome (reverse Takotsubo cardiomyopathy) in a young woman in the setting of amphetamine use. Echocardiography. 2008;25(4):429–432. - PubMed
    1. Song BG, Park S-J, Noh HJ, et al. Clinical characteristics, and laboratory and echocardiographic findings in Takotsubo cardiomyopathy presenting as cardiogenic shock. Journal of Critical Care. 2010;25(2):329–335. - PubMed
    1. Levine RA, Vlahakes GJ, Lefebvre X, et al. Papillary muscle displacement causes systolic anterior motion of the mitral valve: experimental validation and insights into the mechanism of subaortic obstruction. Circulation. 1995;91(4):1189–1195. - PubMed

LinkOut - more resources