Reply: Elevated sputum IL-5 and submucosal eosinophilia in obese individuals with severe asthma

Affiliations

Comment

Dhananjay Desai et al. Am J Respir Crit Care Med. 2014.

. 2014 May 15;189(10):1285-6.

doi: 10.1164/rccm.201402-0294LE.

No abstract available

Comment on

Elevated sputum interleukin-5 and submucosal eosinophilia in obese individuals with severe asthma.
Desai D, Newby C, Symon FA, Haldar P, Shah S, Gupta S, Bafadhel M, Singapuri A, Siddiqui S, Woods J, Herath A, Anderson IK, Bradding P, Green R, Kulkarni N, Pavord I, Marshall RP, Sousa AR, May RD, Wardlaw AJ, Brightling CE. Desai D, et al. Am J Respir Crit Care Med. 2013 Sep 15;188(6):657-63. doi: 10.1164/rccm.201208-1470OC. Am J Respir Crit Care Med. 2013. PMID: 23590263 Free PMC article.
Eosinophilic inflammation in subjects with mild-to-moderate asthma with and without obesity: disparity between sputum and biopsies.
van der Wiel E, Ten Hacken NH, van den Berge M, Timens W, Reddel HK, Postma DS. van der Wiel E, et al. Am J Respir Crit Care Med. 2014 May 15;189(10):1281-4. doi: 10.1164/rccm.201310-1841LE. Am J Respir Crit Care Med. 2014. PMID: 24832748 No abstract available.
Obese individuals with asthma preferentially have a high IL-5/IL-17A/IL-25 sputum inflammatory pattern.
Marijsse GS, Seys SF, Schelpe AS, Dilissen E, Goeminne P, Dupont LJ, Ceuppens JL, Bullens DM. Marijsse GS, et al. Am J Respir Crit Care Med. 2014 May 15;189(10):1284-5. doi: 10.1164/rccm.201311-2011LE. Am J Respir Crit Care Med. 2014. PMID: 24832749 No abstract available.