Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2014 May 12;3(2):333-44.
doi: 10.3390/biology3020333.

High intensity training improves health and physical function in middle aged adults

Affiliations

High intensity training improves health and physical function in middle aged adults

Simon Adamson et al. Biology (Basel). .

Abstract

High intensity training (HIT) is effective at improving health; however, it is unknown whether HIT also improves physical function. This study aimed to determine whether HIT improves metabolic health and physical function in untrained middle aged individuals. Fourteen (three male and eleven female) untrained individuals were recruited (control group n = 6: age 42 ± 8 y, weight 64 ± 10 kg, BMI 24 ± 2 kg·m-2 or HIT group n = 8: age 43 ± 8 y, weight 80 ± 8 kg, BMI 29 ± 5 kg·m-2). Training was performed twice weekly, consisting of 10 × 6-second sprints with a one minute recovery between each sprint. Metabolic health (oral glucose tolerance test), aerobic capacity (incremental time to exhaustion on a cycle ergometer) and physical function (get up and go test, sit to stand test and loaded 50 m walk) were determined before and after training. Following eight weeks of HIT there was a significant improvement in aerobic capacity (8% increase in VO2 peak; p < 0.001), physical function (11%-27% respectively; p < 0.05) and a reduction in blood glucose area under the curve (6% reduction; p < 0.05). This study demonstrates for the first time the potential of HIT as a training intervention to improve skeletal muscle function and glucose clearance as we age.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Change in VO2 peak for control and HIT pre and post intervention. * p < 0.05 pre to post within groups; ** p < 0.001 pre to post within groups; † p < 0.02 magnitude of change between groups.
Figure 2
Figure 2
(a) Time taken to complete a loaded 50m walk test. (b) Time taken to complete a get up and go test. (c) Total number of sit to stands performed in 30 seconds. * p < 0.05 pre to post within groups; ** p < 0.001 pre to post within groups; † p < 0.02 magnitude of change between groups; ‡ p < 0.001magnitude of change between groups.
Figure 3
Figure 3
Change in glucose AUC for control and HIT pre and post intervention. * p < 0.05 pre to post within groups.

References

    1. Short K.R., Vittone J.L., Bigelow M.L., Proctor D.N., Rizza R.A., Coenen-Schmike J.M. Impact of aerobic exercise training on age related changes in insulin sensitivity and muscle oxidative capacity. Diabetes. 2003;52:1888–1896. doi: 10.2337/diabetes.52.8.1888. - DOI - PubMed
    1. Samson M.M., Meeuwsen I.B.A.E., Crowe A., Dessens J.A.G., Duursma S.A., Verhaar H.J.J. Relationships between physical performance measures, age, height and body weight in healthy adults. Age Ageing. 2000;29:235–242. doi: 10.1093/ageing/29.3.235. - DOI - PubMed
    1. Rooyackers O.E., Adey D.B., Ades P.A., Nair K.S. Effect of age on in vivo rates of mitochondrial protein synthesis in human skeletal muscle. Proc. Natl. Acad. Sci. USA. 1996;93:15364–15369. doi: 10.1073/pnas.93.26.15364. - DOI - PMC - PubMed
    1. Pederson B., Saltin B. Evidence for prescribing exercise as therapy in chronic disease. Scand. J. Med. Sci. Sports. 2006;16:3–63. doi: 10.1111/j.1600-0838.2006.00520.x. - DOI - PubMed
    1. Knowler W.C., Barrett-Connor E., Fowler S E., Hamman R F., Lachin J.M., Walker E.A. Diabetes Prevention Program Research Group. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N. Engl. J. Med. 2002;346:393–403. - PMC - PubMed

LinkOut - more resources