Review
. 1989;144(8-9):398-405; discussion 405-6.
[Control and kinetics of intracellular calcium movement in striated muscle]
[Article in
French]
- PMID: 2483352
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Review
[Control and kinetics of intracellular calcium movement in striated muscle]
[Article in
French]
Bull Mem Acad R Med Belg.
1989.
Abstract
The concept of the cytosolic homeostasis of calcium is presented, and the mechanisms by which a very low cytosolic concentration of Ca is maintained are considered. The transient increase of intracellular Ca2+ when muscles fibres are stimulated illustrates the role of Ca as an intracellular messenger. The author presents his own kinetic analysis of the interaction of Ca with several intracellular targets and describes the Ca translocations which take place. Two examples of deficiency in the control of the intracellular Ca2+ are examined: malignant hyperthermia and Duchenne muscular dystrophy.
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