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Review
. 2011 Summer;4(3):102-8.

Subclinical celiac disease and gluten sensitivity

Mohammad Rostami Nejad  1 , Sabine Hogg-Kollars  2 , Sauid Ishaq  3 , Kamran Rostami  4
Affiliations
Review

Subclinical celiac disease and gluten sensitivity

Mohammad Rostami Nejad et al. Gastroenterol Hepatol Bed Bench. 2011 Summer.

Abstract

Atypical presentation is the most common form of celiac disease (CD). Although the terminologies like latent, silent and potential have expressed different aspects of clinical and pathological behaviour of CD, they also have contributed in some extent to confusion between clinicians and patients due to the multiple definitions and uncertainty around them. In the light of new advances and the discovery of entities such as non-celiac gluten sensitivity, using subclinical instead of silent and atypical instead of potential/latent may simplify the understanding behind the clinical behaviour of atypical CD. The evidence behind a lower threshold for starting a gluten free diet (GFD) in non-celiac gluten sensitive patients would strongly support applying a GFD treatment strategy in any forms of CD.

Keywords: Atypical; Celiac disease; Gluten sensitivity; Microscopic enteritis; Subclinical.

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Figures

Figure 1
Figure 1
Celiac and non-celiac gluten sensitivity * Suclinical: previously known as silent and atypical as known under latent and potential CD
See this image and copyright information in PMC

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References

    1. Vilppula A, Collin P, Maki M, Valve R, Luostarinen M, Krekela I, et al. Undetected coeliac disease in the elderly: a biopsy-proven population based study. Dig Liver Dis. 2008;40:809–13. - PubMed
    1. Baudon JJ, Dabadie A, Cardona J, Digeon B, Giniés JL, Larchet M, et al. Incidence of symptomatic celiac disease in French children. Presse Med. 2001;30:107–10. - PubMed
    1. Rostami Nejad, Rostami K, Emami MH, Zali MR, Malekzadeh R. Epidemiology of Celiac disease in Iran; A Review. Middle East Journal of Digestive Diseases. 2011;3:74–77. - PMC - PubMed
    1. Rostami K, Mulder CJ, Werre JM, van Beukelen FR, Kerchhaert J, Crusius JB, Pena AS, Willekens FL, Meijer JW. High prevalence of celiac disease in apparently healthy blood donors suggests a high prevalence of undiagnosed celiac disease in the Dutch population. Scand J Gastroenterol. 1999;34:276–79. - PubMed
    1. Shahbazkhani B, Malekzadeh R, Sotoudeh M, Fayaz Moghadam K, Farhadi M, Ansari R, et al. High prevalence of celiac disease in apparently healthy Iranian blood donors. Eur J Gastroenterol Hepatol. 2003;15:475–78. - PubMed

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