Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2014 Nov-Dec;18(6):660-3.
doi: 10.1016/j.bjid.2014.04.002. Epub 2014 May 15.

Does the change on gastrointestinal tract microbiome affects host?

Affiliations
Review

Does the change on gastrointestinal tract microbiome affects host?

Elisa M Beirão et al. Braz J Infect Dis. 2014 Nov-Dec.

Abstract

During the past decade, studies on the composition of human microbiota and its relation to the host became one of the most explored subjects of the medical literature. The development of high-throughput molecular technologies allowed a deeper characterization of human microbiota and a better understanding of its relationship with health and disease. Changes in human habits including wide use of antimicrobials can result in dysregulation of host-microbiome homeostasis, with multiple consequences. The purpose of this review is to highlight the most important evidence in the literature of host-microbiome interactions and illustrate how these intriguing relations may lead to new treatment and prevention strategies.

Keywords: Gastrintestinal microbiome; Human.

PubMed Disclaimer

References

    1. Blaser M.J. Harnessing the power of the human microbiome. Proc Natl Acad Sci USA. 2010;107:6125–6126. - PMC - PubMed
    1. Kuczynski J., Lauber C.L., Walters W.A., et al. Experimental and analytical tools for studying the human microbiome. Nat Rev Genet. 2011;13:47–58. - PMC - PubMed
    1. Human Microbiome Project Consortium Structure, function and diversity of the healthy human microbiome. Nature. 2012;486:207–214. - PMC - PubMed
    1. Stearns J.C., Lynch M.D., Senadheera D.B., et al. Bacterial biogeography of the human digestive tract. Sci Rep. 2011;1:170. - PMC - PubMed
    1. Muegge B.D., Kuczynski J., Knights D., et al. Diet drives convergence in gut microbiome functions across mammalian phylogeny and within humans. Science. 2011;332:970–974. - PMC - PubMed

MeSH terms