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Comment
. 2014 May 15;40(5):635-7.
doi: 10.1016/j.immuni.2014.04.017.

Amino acids fuel T cell-mediated inflammation

Maya C Poffenberger  1 , Russell G Jones  2
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Amino acids fuel T cell-mediated inflammation

Maya C Poffenberger et al. Immunity. .
Free article

Abstract

Reprogramming cellular metabolism helps support T cell growth and effector function upon activation. In this issue of Immunity, Nakaya et al. (2014) report that the glutamine transporter ASCT2 regulates T cell metabolism and mTOR kinase signaling to shape inflammatory T helper cell responses.

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