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Randomized Controlled Trial
. 2014 May 15;11(5):5273-93.
doi: 10.3390/ijerph110505273.

Evaluation of a school-based depression prevention program among adolescents from low-income areas: a randomized controlled effectiveness trial

Karlijn C M Kindt  1 , Marloes Kleinjan  2 , Jan M A M Janssens  3 , Ron H J Scholte  4
Affiliations
Randomized Controlled Trial

Evaluation of a school-based depression prevention program among adolescents from low-income areas: a randomized controlled effectiveness trial

Karlijn C M Kindt et al. Int J Environ Res Public Health. .

Abstract

A randomized controlled trial was conducted among a potential high-risk group of 1,343 adolescents from low-income areas in The Netherlands to test the effectiveness of the depression prevention program Op Volle Kracht (OVK) as provided by teachers in a school setting. The results showed no main effect of the program on depressive symptoms at one-year follow-up. A moderation effect was found for parental psychopathology; adolescents who had parents with psychopathology and received the OVK program had less depressive symptoms compared to adolescents with parents with psychopathology in the control condition. No moderating effects on depressive symptoms were found for gender, ethnical background, and level of baseline depressive symptoms. An iatrogenic effect of the intervention was found on the secondary outcome of clinical depressive symptoms. Based on the low level of reported depressive symptoms at baseline, it seems that our sample might not meet the characteristics of a high-risk selective group for depressive symptoms. Therefore, no firm conclusions can be drawn about the selective potential of the OVK depression prevention program. In its current form, the OVK program should not be implemented on a large scale in the natural setting for non-high-risk adolescents. Future research should focus on high-risk participants, such as children of parents with psychopathology.

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Figures

Figure 1
Figure 1
Flow diagram.
Figure 2
Figure 2
Interaction effect for adolescents with/without parents with psychopathology and the intervention.
See this image and copyright information in PMC

References

    1. Kessler R.C., Petukhova M., Sampson N.A., Zaslavsky A.M., Wittchen H.U. Twelve-month and lifetime prevalence and lifetime morbid risk of anxiety and mood disorders in the United States. Int. J. Method. Psychiatr. Res. 2012;21:169–184. doi: 10.1002/mpr.1359. - DOI - PMC - PubMed
    1. Twenge J.M., Nolen-Hoeksema S. Age, gender, race, socioeconomic status, and birth cohort difference on the children’s depression inventory: A meta-analysis. J. Abnorm. Psychol. 2002;111 doi: 10.1037/0021-843X.111.4.578. - DOI - PubMed
    1. Gillham J.E., Reivich K.J., Freres D.R., Chaplin T.M., Shatté A.J., Samuels B., Elkon A.G.L., Litzinger S, Lascher M, Gallop R, Seligman M.E.P. School-based prevention of depressive symptoms: A randomized controlled study of the effectiveness and specificity of the Penn Resiliency Program. J. Consult. Clin. Psychol. 2007;75:1–19. doi: 10.1037/0022-006X.75.1.1. - DOI - PMC - PubMed
    1. Pössel P., Horn A.B., Groen G., Hautzinger M. School-based prevention of depressive symptoms in adolescents: A 6-month follow-up. J. Amer. Acad. Child. Adolesc. Psy. 2004;43:1003–1010. doi: 10.1097/01.chi.0000126975.56955.98. - DOI - PubMed
    1. Clarke G.N., Hawkins W., Murphy M., Sheeber L.B., Lewinsohn P.M., Seeley J.R. Targeted prevention of unipolar depressive disorder in an at-risk sample of high school adolescents: A randomized trial of a group cognitive intervention. J. Amer. Acad. Child. Adolesc. Psy. 1995;34:312–321. doi: 10.1097/00004583-199503000-00016. - DOI - PubMed

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