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Randomized Controlled Trial
. 2014 Aug;165(2):398-400.e3.
doi: 10.1016/j.jpeds.2014.04.007. Epub 2014 May 14.

School-age outcomes following a randomized controlled trial of magnesium sulfate for neuroprotection of preterm infants

Clément Chollat  1 , Maya Enser  2 , Estelle Houivet  3 , Delphine Provost  2 , Jacques Bénichou  3 , Loïc Marpeau  4 , Stéphane Marret  5
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Randomized Controlled Trial

School-age outcomes following a randomized controlled trial of magnesium sulfate for neuroprotection of preterm infants

Clément Chollat et al. J Pediatr. 2014 Aug.

Abstract

In a French randomized trial, children at school-age demonstrated no evidence of harm from fetal exposure to MgSO4 before very preterm birth. Motor dysfunction/death, qualitative behavioral disorders, cognitive difficulties, school grade repetition, and education services were decreased in the children exposed to MgSO4, although the differences were not significant.

Trial registration: ClinicalTrials.gov NCT00120588.

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