Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2014 Apr;34(2):146-9.

Auricular involvement of a multifocal non-AIDS Kaposi's sarcoma: a case report

Affiliations
Case Reports

Auricular involvement of a multifocal non-AIDS Kaposi's sarcoma: a case report

M Busi et al. Acta Otorhinolaryngol Ital. 2014 Apr.

Abstract

Kaposi's sarcoma (KS) is a multicentric, malignant neoplastic vascular disease, mainly involving skin and mucosae, characterised by the proliferation of endothelial cells. The aetiology of KS still is unknown. Nonetheless, it has been reported that several epidemiological and environmental factors may play a role in its pathogenesis. Viral factors (i.e. human herpes virus 8, HHV-8) have also been claimed to play a role in the onset of KS. Four main clinical presentations of KS have been described: classic (sporadic), African (endemic), iatrogenic (immunosuppression-associated) and AIDS-associated (epidemic). The authors present a case of KS involving the external ear of a HIVnegative patient with a history of non-Hodgkin lymphoma and tuberculosis.

Il Sarcoma di Kaposi (KS) è una patologia neoplastica maligna su base vascolare, che principalmente coinvolge la cute e le mucose, caratterizzata dalla proliferazione di cellule endoteliali. L'eziologia del KS è ancora sconosciuta, sebbene sia stato riportato che fattori epidemiologici, ambientali e virali (es Herpes virus umano 8, HHV-8) possano avere un ruolo nella patogenesi di tale affezione. Ad oggi, sono state descritte quattro forme principali di KS: classico (sporadico), africano (endemico), iatrogeno (associato a stati di immunosoppressione) ed AIDS-relato (epidemico). Gli Autori presentano un caso di KS con coinvolgimento del condotto uditivo esterno, in una paziente HIV-negativa con storia di linfoma non-Hodgkin e tubercolosi.

Keywords: External ear; Kaposi's sarcoma; Lymphoproliferative disorders.

PubMed Disclaimer

Figures

Fig. 1.
Fig. 1.
Lesion of the external ear involving the concha.
Fig. 2.
Fig. 2.
Multiple skin lesions on the right arm.

Similar articles

Cited by

References

    1. Kaposi M. Idiopathisches multiples Pigmentsarkom der Haut. Arch Dermatol Syph. 1872;4:265–273.
    1. Ramírez-Amador V, Martínez-Mata G, González-Ramírez I, et al. Clinical, histological and immunohistochemical findings in oral Kaposi's sarcoma in a series of Mexican AIDS patients. Comparative study. J Oral Pathol Med. 2009;38:328–333. - PubMed
    1. Feller L, Lemmer J, Wood NH, et al. HIV-associated oral Kaposi sarcoma and HHV-8: a review. J Int Acad Periodontol. 2007;9:129–136. - PubMed
    1. Fletcher CD, Unni KK, Mertens F, Lamovec J, et al. Kaposi sarcoma. In: Fletcher CD, Unni KK, Mertens F, editors. Pathology and genetics of tumours of soft tissue and bone. World Health Organization classification of tumours. Lyon, France: IARC Press; 2002. pp. 170–172.
    1. Schwartz RA. Kaposi's sarcoma: an update. J Surg Oncol. 2004;87:146–151. - PubMed

Publication types

LinkOut - more resources