Auricular involvement of a multifocal non-AIDS Kaposi's sarcoma: a case report
- PMID: 24843227
- PMCID: PMC4025183
Auricular involvement of a multifocal non-AIDS Kaposi's sarcoma: a case report
Abstract
Kaposi's sarcoma (KS) is a multicentric, malignant neoplastic vascular disease, mainly involving skin and mucosae, characterised by the proliferation of endothelial cells. The aetiology of KS still is unknown. Nonetheless, it has been reported that several epidemiological and environmental factors may play a role in its pathogenesis. Viral factors (i.e. human herpes virus 8, HHV-8) have also been claimed to play a role in the onset of KS. Four main clinical presentations of KS have been described: classic (sporadic), African (endemic), iatrogenic (immunosuppression-associated) and AIDS-associated (epidemic). The authors present a case of KS involving the external ear of a HIVnegative patient with a history of non-Hodgkin lymphoma and tuberculosis.
Il Sarcoma di Kaposi (KS) è una patologia neoplastica maligna su base vascolare, che principalmente coinvolge la cute e le mucose, caratterizzata dalla proliferazione di cellule endoteliali. L'eziologia del KS è ancora sconosciuta, sebbene sia stato riportato che fattori epidemiologici, ambientali e virali (es Herpes virus umano 8, HHV-8) possano avere un ruolo nella patogenesi di tale affezione. Ad oggi, sono state descritte quattro forme principali di KS: classico (sporadico), africano (endemico), iatrogeno (associato a stati di immunosoppressione) ed AIDS-relato (epidemico). Gli Autori presentano un caso di KS con coinvolgimento del condotto uditivo esterno, in una paziente HIV-negativa con storia di linfoma non-Hodgkin e tubercolosi.
Keywords: External ear; Kaposi's sarcoma; Lymphoproliferative disorders.
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