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. 1989:23:145-50.
doi: 10.1007/BF02917185.

Biological activity of some Schiff bases and their metal complexes

R K Parashar  1 , R C Sharma, G Mohan
Affiliations

Biological activity of some Schiff bases and their metal complexes

R K Parashar et al. Biol Trace Elem Res. 1989.

Abstract

Schiff bases derived from salicylaldehyde and 2-substituted aniline and their metal chelates with Cu(II), Ni(II), and Co(II) ions were synthesized and screened for the antiinflammatory and antiulcer activity. The compound salicylidene-anthranilic acid (SAA) was found to possess the antiinflammatory and antiulcer activity. The copper complexes showed an increased antiulcer activity. The SAA is perhaps acting by influencing prostaglandin biosynthesis.

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