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. 1989 Apr;3(2):186-8.
doi: 10.1007/BF00852907.

Hypogammaglobulinemia in children undergoing continuous ambulatory peritoneal dialysis

B A Fivush  1 , B Case, M W May, H M Lederman
Affiliations

Hypogammaglobulinemia in children undergoing continuous ambulatory peritoneal dialysis

B A Fivush et al. Pediatr Nephrol. 1989 Apr.

Abstract

Humoral immunity was evaluated in seven children undergoing continuous ambulatory peritoneal dialysis (CAPD). Five children (71%) had serum immunoglobulin levels which were more than 2 SD below the mean for age. One mechanism contributing to hypogammaglobulinemia was loss via the peritoneal membrane. Daily losses of IgG into peritoneal dialysis effluents represented 7%-29% of normal daily IgG synthesis, and losses increased with duration of CAPD therapy. Despite the observed hypogammaglobulinemia, all children had protective antibody responses to immunization.

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References

    1. Kidney Int. 1981 Apr;19(4):593-602 - PubMed
    1. J Pediatr. 1987 Oct;111(4):513-8 - PubMed
    1. Kidney Int. 1984 Sep;26(3):253-62 - PubMed
    1. Trans Am Soc Artif Intern Organs. 1978;24:484-9 - PubMed
    1. Prog Allergy. 1969;13:1-110 - PubMed

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