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. 2014 Jul;24(7):374-80.
doi: 10.1097/FPC.0000000000000057.

PharmGKB summary: tramadol pathway

Li Gong  1 , Ulrike M Stamer, Mladen V Tzvetkov, Russ B Altman, Teri E Klein
Affiliations

PharmGKB summary: tramadol pathway

Li Gong et al. Pharmacogenet Genomics. 2014 Jul.
No abstract available

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Conflict of interest statement

Conflicts of interest

There are no conflicts of interest.

Figures

Fig. 1
Fig. 1
Stylized liver cell showing candidate genes involved in the metabolism and transport of tramadol. A fully interactive version is available online at http://www.pharmgkb.org/pathway/PA165946349.
See this image and copyright information in PMC

References

    1. Reeves RR, Burke RS. Tramadol: basic pharmacology and emerging concepts. Drugs Today (Barc) 2008;44:827–836. - PubMed
    1. Leppert W. Tramadol as an analgesic for mild to moderate cancer pain. Pharmacol Rep. 2009;61:978–992. - PubMed
    1. Scott LJ, Perry CM. Tramadol: a review of its use in perioperative pain. Drugs. 2000;60:139–176. - PubMed
    1. Beaulieu AD, Peloso PM, Haraoui B, Bensen W, Thomson G, Wade J, et al. Once-daily, controlled-release tramadol and sustained-release diclofenac relieve chronic pain due to osteoarthritis: a randomized controlled trial. Pain Res Manag. 2008;13:103–110. - PMC - PubMed
    1. Kanaan M, Daali Y, Dayer P, Desmeules J. Uptake/efflux transport of tramadol enantiomers and O-desmethyltramadol: focus on P-glycoprotein. Basic Clin Pharmacol Toxicol. 2009;105:199–206. - PMC - PubMed

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