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. 2010 Dec;51(Suppl 5):18.
doi: 10.1111/j.1528-1167.2010.02804.x.

Neocortical synchronization

Igor Timofeev  1 , Maksim Bazhenov  2 , Joseé Seigneur  1 , Terrence Sejnowski  3
Affiliations

Neocortical synchronization

Igor Timofeev et al. Epilepsia. 2010 Dec.

Abstract

Neuronal synchronization occurs when two or more neuronal events are coordinated across time. Local synchronization produces field potentials. Long-range synchronization between distant brain sites contributes to the electroencephalogram. Neuronal synchronization depends on synaptic (chemical/electrical), ephaptic, and extracellular interactions. For an expanded treatment of this topic see Jasper's Basic Mechanisms of the Epilepsies, Fourth Edition (Noebels JL, Avoli M, Rogawski MA, Olsen RW, Delgado-Escueta AV, eds) published by Oxford University Press (available on the National Library of Medicine Bookshelf [NCBI] at www.ncbi.nlm.nih.gov/books).

Keywords: Epilepsy; Extracelullar conditions; Feedback loops; Local synchronization; Long-range synchronization; Oscillations; Propagating activities; Seizures.

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Conflict of interest statement

Disclosure

The authors declare no conflicts of interest.

References

    1. Bazhenov M, Timofeev I. Thalamocortical oscillations. 2006 http://www.scholarpedia.org/article/Thalamocortical_Oscillations.
    1. Steriade M, McCormick DA, Sejnowski TJ. Thalamocortical oscillations in the sleeping and aroused brain. Science. 1993;262:679–685. - PubMed
    1. Timofeev I, Bazhenov M, Seigneur J, Sejnowski T. Neocortical synchronization. In: Noebels JL, Avoli M, Rogawski MA, Olsen RW, Delgado-Escueta AV, editors. Jasper's basic mechanisms of the epilepsies. 4th ed. New York: Oxford University Press; 2011. [in press]. - PubMed