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Review
. 2014 Dec;35(12):2215-26.
doi: 10.3174/ajnr.A3917. Epub 2014 May 22.

Gadolinium contrast agents for CNS imaging: current concepts and clinical evidence

E Kanal  1 , K Maravilla  2 , H A Rowley  3
Affiliations
Review

Gadolinium contrast agents for CNS imaging: current concepts and clinical evidence

E Kanal et al. AJNR Am J Neuroradiol. 2014 Dec.

Abstract

The aim of this article was to review the properties of the various gadolinium-based contrast agents used for CNS imaging along with the clinical evidence and published data that highlight the impact these different properties can have on diagnostic performance. In addition, approaches to optimizing image acquisition that take into account the different properties of specific gadolinium-based contrast agents and an extensive review of the safety profiles of the various agents are presented.

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Figures

Fig 1.
Fig 1.
Comparison of T1 shortening of GBCAs as a function of Gd concentration, calculated from the r1-relaxivities in blood reported by Rohrer et al in 2005.
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