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Case Reports
. 2014 Nov;33(11):1191-3.
doi: 10.1097/INF.0000000000000412.

Two cases of neonatal human parechovirus 3 encephalitis

Elena Pariani  1 , Laura Pellegrinelli, Lorenza Pugni, Paolo Bini, Simona Perniciaro, Laura Bubba, Valeria Primache, Antonella Amendola, Mario Barbarini, Fabio Mosca, Sandro Binda
Affiliations
Case Reports

Two cases of neonatal human parechovirus 3 encephalitis

Elena Pariani et al. Pediatr Infect Dis J. 2014 Nov.

Abstract

We report 2 neonates with human parechoviruses type 3 encephalitis. Both newborns presented with fever, irritability and seizures. Cerebrospinal fluid analyses were normal, but magnetic resonance imaging revealed white matter damage, suggesting human parechoviruse infection. Human parechoviruses type 3-RNA was detected in cerebrospinal fluid samples and in blood, stool, urine and respiratory samples, indicating the dissemination of the virus.

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