Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2014 May 21;82(4):728-30.
doi: 10.1016/j.neuron.2014.05.012.

Blood-brain barrier: a dual life of MFSD2A?

Zhen Zhao  1 , Berislav V Zlokovic  2
Affiliations
Comment

Blood-brain barrier: a dual life of MFSD2A?

Zhen Zhao et al. Neuron. .

Abstract

Two recent papers in Nature, Ben-Zvi et al. (2014) and Nguyen et al. (2014), report a surprising dual role for the blood-brain barrier transporter MFSD2A in both establishing BBB integrity and in uptake of the fatty acid DHA.

PubMed Disclaimer

Figures

Figure 1
Figure 1. The Neurovascular Unit and Blood-Brain Barrier
See this image and copyright information in PMC

Comment on

References

    1. Armulik A, Genové G, Mäe M, Nisancioglu MH, Wallgard E, Niaudet C, He L, Norlin J, Lindblom P, Strittmatter K, et al. Nature. 2010;468:557–561. - PubMed
    1. Bell RD, Winkler EA, Sagare AP, Singh I, LaRue B, Deane R, Zlokovic BV. Neuron. 2010;68:409–427. - PMC - PubMed
    1. Bell RD, Winkler EA, Singh I, Sagare AP, Deane R, Wu Z, Holtzman DM, Betsholtz C, Armulik A, Sallstrom J, et al. Nature. 2012;485:512–516. - PMC - PubMed
    1. Ben-Zvi A, Lacoste B, Kur E, Andreone BJ, Mayshar Y, Yan H, Gu C. Nature. 2014 Published online May 14, 2014 http://dx.doi.org/10.1038/nature13324. - DOI - PMC - PubMed
    1. Blinder P, Tsai PS, Kaufhold JP, Knutsen PM, Suhl H, Kleinfeld D. Nat Neurosci. 2013;16:889–897. - PMC - PubMed

Substances

LinkOut - more resources