Comment
doi: 10.1016/j.chembiol.2014.05.001.
Polarity factors play a role in antibiotic resistance
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- PMID: 24856139
- DOI: 10.1016/j.chembiol.2014.05.001
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Comment
Polarity factors play a role in antibiotic resistance
Chem Biol.
.
Abstract
In this issue of Chemistry & Biology, Kirkpatrick and Viollier describe a new twist in the relationship between bacterial cell development and antibiotic resistance. They reveal that TipN, which orchestrates development at cell poles, is required to tolerate induced expression of an antibiotic efflux pump.
Copyright © 2014 Elsevier Ltd. All rights reserved.
Comment on
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Synthetic interaction between the TipN polarity factor and an AcrAB-family efflux pump implicates cell polarity in bacterial drug resistance.Chem Biol. 2014 May 22;21(5):657-65. doi: 10.1016/j.chembiol.2014.02.018. Epub 2014 Apr 10. Chem Biol. 2014. PMID: 24726830
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